Stem Cell CSD inhibitor Set
Axon 5006
CAS [N.A.]
MF #N/AMW #N/A
- Purity:99%
- Soluble in DMSO
Description
A convenient set of three small molecule inhibitors, GSK-3 inhibitor CHIR 99021 (Axon 1386), FGFR inhibitor SU 5402 (Axon 1667) and gamma secretase inhibitor DAPT (Axon 1484) (termed as CSD or neuronal 3i). CHIR 99021 is the key factor for inducing neuronal differentiation, whereas SU 5402 and DAPT further enhance efficiency.
Combination of stem cell CSD (neuronal 3i) inhibitor set with LSB inhibitor set (Axon 5004) forms stem cell 5i inhibitor set (Axon 5007, aka LSB3i or LSB+3i), which was used for rapid and efficient differentiation of human pluripotent stem cells (hPSCs) into nociceptors.
Read more: Additional Product Information
Show all Axon Ligand™Sets
| S.M. Chambers et al. Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nature Biotechnol. 2012, 30, 715-720. |
List of publications using CHIR 99021 (Axon 1386) purchased from Axon Medchem
- Certificate of Analysis
- Material Safety Data Sheet
- Additional Product Information
Chemical name
N.A.
Parent CAS No.
[N.A.]
