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商品详细axonmedchem/干细胞替代2i抑制剂组/每个2 mg/Axon 2130
axonmedchem/干细胞替代2i抑制剂组/每个2 mg/Axon 2130
axonmedchem/干细胞替代2i抑制剂组/每个2 mg/Axon 2130
商品编号: Axon2130
品牌: axon medch
市场价: ¥2000.00
美元价: 1000.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
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商品介绍

Stem Cell Alternative 2i inhibitor Set

Based on 18 reference(s) in Google Scholar91018

Axon 2130

CAS [N.A.]

MF N.A.MW N.A.

  • Purity:99%
  • Soluble in DMSO

Stem Cell Alternative 2i inhibitor Set

Description

A convenient set of SRC inhibitor CGP 77675 (Axon 2097) and GSK-3 inhibitor CHIR 99021 (Axon 1386); an alternative 2i inhibitor set vs the conventional 2i inhibitor set (Axon 2128) of MEK inhibitor PD 0325901 and GSK3 inhibitor CHIR 99021.

The dual inhibition of Src and GSK-3 signaling by CGP 77675 and CHIR 99021 (termed alternative 2i) was found to maintain mouse embryonic stem cell (mESC) self-renewal and pluripotency marker expression as efficiently as the dual inhibition of MAPK and GSK-3 by PD 0325901 and CHIR 99021 (conventional 2i, Axon 2128). This alternative 2i method provides a versatile tool not only for the maintenance of mESCs in serum-free conditions but also for the derivation of ESCs from mouse embryos.

Read more:Additional Product Information

Show all Axon Ligand™Sets

T. Shimizu et al. Dual inhibition of Src and GSK3 maintains mouse embryonic stem cells, whose differentiation is mechanically regulated by Src signaling. Stem Cells 2012, 30, 1394-1404.
  • Certificate of Analysis
  • Material Safety Data Sheet
  • Additional Product Information
Cell Signaling & OncologyCNSDiabetes & MetabolismImmunologyPain & InflammationStem CellGSK-3SRCWnt-β-CateninPI3K-Akt-mTORStem Cells
Set of SRC inhibitor CGP77675 (Axon 2097) and GSK-3 inhibitor CHIR99021 (Axon 1386)

Chemical name

N.A.

Parent CAS No.

[N.A.]

品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来,是欧洲**的化学服务平台,专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织(CRO)进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源,提供药品研究用的Axon Ligands (TM)系列。