商品详细axonmedchem/干细胞4i抑制剂组-iPSC TSPC抑制剂组
axonmedchem/干细胞4i抑制剂组-iPSC TSPC抑制剂组
市场价：
¥3400.00
美元价：
1700.00
商品介绍
Stem Cell 4i inhibitor Set - iPSC-TSPC inhibitor Set
Based on 18 reference(s) in Google Scholar101018
Axon 5009
CAS [N.A.]
MF #N/AMW #N/A
- Purity:99%
- Soluble in DMSO
Description
A convenient set of four small molecule pathway inhibitors, ROCK inhibitor Thiazovivin (Axon 1535), TGF-β inhibitor SB 431542 (Axon 1661), MEK inhibitor PD 0325901 (Axon 1408) and GSK-3 inhibitor CHIR 99021 (Axon 1386) (termed as stem cell 4i or iPSC-TSPC). The small molecule cocktail of 4 inhibitors (SMC4) was reported to efficiently generate, characterize and maintain single cell and feeder-free (FF) cultural human induced pluripotent stem cells (iPSCs, or hiPSCs), hence a high-throughput reprogramming platform.
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- References
- Certificates
- Categories
- Extra info
| S.M. Chambers et al. Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nature Biotechnol. 2012, 30, 715-720. |
List of publications using PD 0325901 (Axon 1408) purchased from Axon Medchem
List of publications using CHIR 99021 (Axon 1386) purchased from Axon Medchem
- Certificate of Analysis
- Material Safety Data Sheet
- Additional Product Information
ApoptosisCell Signaling & OncologyCNSDiabetes & MetabolismImmunologyPain & InflammationStem CellGSK-3ROCKWnt-β-CateninTGF-βMAPKPI3K-Akt-mTORStem CellsMEKTGF-βR
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
