商品详细axonmedchem/原始干细胞NHSM抑制剂组-干细胞6i抑制剂组
axonmedchem/原始干细胞NHSM抑制剂组-干细胞6i抑制剂组
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¥4600.00
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2300.00
商品介绍
Naive Stem Cell NHSM inhibitor Set - Stem Cell 6i inhibitor Set
Based on 12 reference(s) in Google Scholar101012
Axon 5010
CAS [N.A.]
MF #N/AMW #N/A
- Purity:99%
- Soluble in DMSO
Description
A convenient set of six small molecule pathway inhibitors (termed as Naive stem cell 6i or NHSM inhibitors): - GSK3 inhibitor CHIR 99021 (Axon 1386) - MEK inhibitor PD 0325901 (Axon 1408) - p38 inhibitor BIRB 796 (Axon 1358) - JNK inhibitor SP 600125 (Axon 2519) - PKC inhibitor Gö 6983 (Axon 2466) - ROCK inhibitor Y 27632 dihydrochloride (Axon 1683) These 6 small molecule inhibitors were used in the basic NHSM composition as published in Nature 2013 by Gafni et al. and with modifications at Hanna lab, the Weizmann Institute of Science (WIS). Useful tool for isolation, generation, derivatization and stabilization of naive human pluripotent stem cells.
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KEYWORDS: Naïve Stem Cell NHSM inhibitor Set | supplier | Stem cell inhibitor set | Stem Cell 6i inhibitor Set | CHIR99021 | PD0325901 | BIRB796 | SP600125 | GO6983 | CAS [252917-06-9] | [391210-10-9] | [285983-48-4] | [129-56-6] | [129-56-6] | [133053-19-7] | GSK3 | MEK | p38 | JNK | PKC | ROCK | Inhibitor | Axon Ligand Set | NHSM composition | Gafni | Hanna | Weizmann Institute of Science | WIS | isolation | generation | derivatization | stabilization | naive | human | pluripotent | stem cells |NSC
- References
- Certificates
- Categories
- Extra info
| O. Gafni et al. Derivation of novel human ground state naive pluripotent stem cells. Nature. 2013 Dec 12;504(7479):282-6. |
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| Hanna Lab, WIS-NHSM human naive medium formulation & protocols |
List of publications using CHIR 99021 (Axon 1386) purchased from Axon Medchem
List of publications using PD 0325901 (Axon 1408) purchased from Axon Medchem
List of publications using BIRB 796 - Doramapimod (Axon 1358) purchased from Axon Medchem
List of publications using Y 27632 dihydrochloride (Axon 1683) purchased from Axon Medchem
- Certificate of Analysis
- Material Safety Data Sheet
- Additional Product Information
Cell Signaling & OncologyCNSDiabetes & MetabolismImmunologyPain & InflammationStem CellGSK-3ROCKMAPK (JNK)MAPK (p38)Wnt-β-CateninPI3K-Akt-mTORStem CellsMEKPKC
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
