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当前位置: 首页 > 产品中心 > juhewu > axonmedchem/AMD 3100-Plerixafor | SID 791 | JM 3100
商品详细axonmedchem/AMD 3100-Plerixafor | SID 791 | JM 3100
axonmedchem/AMD 3100-Plerixafor | SID 791 | JM 3100
axonmedchem/AMD 3100-Plerixafor | SID 791 | JM 3100
商品编号: Axon1738
品牌: axon medch
市场价: ¥1700.00
美元价: 850.00
产地: 美国(厂家直采)
公司:
产品分类: 聚合物
公司分类: juhewu
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

AMD 3100 - Plerixafor | SID 791 | JM 3100

Based on 15 reference(s) in Google Scholar81015

Axon 1738

CAS [155148-31-5]

MF C28H54N8.8HClMW 794.47

  • Purity:100%
  • Soluble in water

AMD 3100

Description

Highly potent and selective chemokine CXCR4 receptor antagonist, with IC50 values to be 0.02-0.13 and >25 μM for CXCR4 and all other chemokine receptors respectively); HIV inhibitor; an immunostimulant used to multiply hematopoietic stem cells in cancer patients
E De Clercq et al. Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100. Antimicrob. agents chemother. 1994, 38(4), 668–74.
SL Davies et al. Plerixafor Hydrochloride. Drugs Fut. 2007,32(2), 123.
AF Cashen et al. AMD3100: CXCR4 antagonist and rapid stem cell-mobilizing agent. Future Oncol. 2007, 3(1), 19–27.
G Calandra et al. AMD3100 plus G-CSF can successfully mobilize CD34+ cells from non-Hodgkin"s lymphoma, Hodgkin"s disease and multiple myeloma patients previously failing mobilization with chemotherapy (...). Bone Marrow Transpl. 2008, 41, 331–338.
  • Certificate of Analysis
  • Material Safety Data Sheet
Cell Signaling & OncologyImmunologyStem CellImmunomodulatorA2Chemokine
CXCR4 antagonist

Chemical name

1,4-bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene octahydrochloride

Parent CAS No.

[110078-46-1]

品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来,是欧洲**的化学服务平台,专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织(CRO)进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源,提供药品研究用的Axon Ligands (TM)系列。