axonmedchem/BAY-876/5毫克/Axon 2660
商品编号：
Axon2660
品牌：
axon medch
市场价：
¥2100.00
美元价：
1050.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BAY-876
Axon 2660
CAS [1799753-63-1]
MF C24H16F4N6O2MW 496.42
- Purity:99%
- Soluble in DMSO
Description
BAY-876 is a higly selective GLUT1 inhibitor (IC50 value 2 nM). In vitro PK data showed that BAY-876 was very stable in liver microsomes and hepatocytes; preliminary in vivo PK studies demonstrated a good oral bioavailability and long terminal half-life.
KEYWORDS: BAY-876 | supplier | GLUT1 inhibitor | BAY876 | BAY 876 | CAS [1799753-63-1] | Glucose | GLUT1 | Inhibitor | Proteins | Transporter | Glucose Transporter 1
| H Siebeneicher et al. Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876. ChemMedChem. 2016 Oct 19;11(20):2261-2271. |
- Certificate of Analysis
- Material Safety Data Sheet
Cell Signaling & OncologyDiabetes & MetabolismGLUT1
Inhibitor of glucose transporter 1 (GLUT1)
Chemical name
N4-(1-(4-Cyanobenzyl)-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-7-fluoroquinoline-2,4-dicarboxamide
Parent CAS No.
[1799753-63-1]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
