axonmedchem/BAM 7/10毫克/轴突2185
商品编号：
Axon2185
品牌：
axon medch
市场价：
¥1800.00
美元价：
900.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BAM 7
Axon 2185
CAS [331244-89-4]
MF C21H19N5O2SMW 405.47
- Purity:98%
- Soluble in DMSO
Description
Selective small-molecule activator of proapoptotic BAX (IC50 value 3.3 μM) that binds to the BH3 binding domain without interacting with other BH3-binding pockets of antiapoptotic proteins or proapoptotic BAK. BAM 7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and BAX-dependent cell death.
| E. Gavathiotis et al. Direct and selective small-molecule activation of proapoptotic BAX. Nat. Chem. Biol. 2012, 8, 639-645. |
- Certificate of Analysis
- Material Safety Data Sheet
ApoptosisCell Cycle RegulationCell Signaling & Oncologyp53-Tumor SuppressionBcl
Selective small-molecule activator of proapoptotic BAX
Chemical name
4-(2-(2-ethoxyphenyl)hydrazono)-3-methyl-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5(4H)-one
Parent CAS No.
[331244-89-4]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
