axonmedchem/AT 406-SM 406/5 mg/轴突1985
商品编号：
Axon1985
品牌：
axon medch
市场价：
¥2900.00
美元价：
1450.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
AT 406 - SM 406
Axon 1985
CAS [1071992-99-8]
MF C32H43N5O4MW 561.71
- Purity:100%
- Optical purity:Optically pure
- Soluble in DMSO
Description
Potent and orally available antagonist of the inhibitor of apoptosis proteins (IAPs); binds to XIAP, cIAP1, and cIAP2 proteins with Ki of 66.4, 1.9, and 5.1 nM, respectively
| Q Cai et al. A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment. J. Med. Chem. 2011, 54 (8), 2714–2726. |
- Certificate of Analysis
- Material Safety Data Sheet
ApoptosisCell Cycle RegulationCell Signaling & OncologyIAP
Antagonist of Inhibitor of apoptosis proteins (IAPs)
Chemical name
(5S,8S,10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide
Parent CAS No.
[1071992-99-8]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
