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商品详细axonmedchem/ARN 272/5毫克/轴突2941
axonmedchem/ARN 272/5毫克/轴突2941
axonmedchem/ARN 272/5毫克/轴突2941
商品编号: Axon2941
品牌: axon medch
市场价: ¥1800.00
美元价: 900.00
产地: 美国(厂家直采)
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产品分类: 聚合物
公司分类: juhewu
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商品介绍

ARN 272

Based on 3 reference(s) in Google Scholar8103

Axon 2941

CAS [488793-85-7]

MF C27H20N4O2MW 432.47

  • Purity:98%
  • Soluble in DMSO

ARN 272

Description

ARN 272 is a selective competitive antagonist of the interaction of anandamide with FAAH-like anandamide transporter (IC50 value of 1.8 µM). Moreover, ARN 272 prevents anandamide internalization in vitro, interrupts anandamide deactivation in vivo, and exerts profound analgesic effects in rodent models of nociceptive and inflammatory pain, which are mediated by CB1 cannabinoid receptors.

KEYWORDS: ARN 272 | supplier | FLAT inhibitor | ARN272 | ARN-272 | CAS [488793-85-7] | Fatty acid (Amides) | FLAT | Inhibitor | Proteins | FAAH-1

J Fu et al. A catalytically silent FAAH-1 variant drives anandamide transport in neurons. Nat Neurosci. 2011 Nov 20;15(1):64-9.
  • Certificate of Analysis
  • Material Safety Data Sheet
CNSPain & InflammationFAAHFLAT
Selective inhibitor of FAAH-like anandamide transporter (FLAT)

Chemical name

4-(4-(4-Hydroxyphenyl)phthalazin-1-ylamino)-N-phenylbenzamide

Parent CAS No.

[488793-85-7]

品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来,是欧洲**的化学服务平台,专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织(CRO)进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源,提供药品研究用的Axon Ligands (TM)系列。