axonmedchem/（R）-CE3F4/5毫克/轴突2830
商品编号：
Axon2830
品牌：
axon medch
市场价：
¥2100.00
美元价：
1050.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
(R)-CE3F4
Axon 2830
CAS [1593478-56-8]
MF C11H10Br2FNOMW 351.01
- Purity:99%
- Optical purity:98% e.e.
- Soluble in DMSO
Description
(R)-CE3F4 is an inhibitor of EPAC1 (IC50 value of 5.8 µM) with a 10-fold selectivity for EPAC1 over EPAC2. (R)-CE3F4 prevents EPAC1 activation in vitro and in living cultured cells by inhibiting the GEF activity of EPAC1. Racemic CE3F4 is available as Axon 2929.
KEYWORDS: (R)-CE3F4 | supplier | EPAC1 inhibitor | CAS [1593478-56-8] | cAMP | EPAC | Inhibitor | Proteins
| D Courilleau et al. The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1). Biochem Biophys Res Commun. 2013 Oct 25;440(3):443-8. |
- Certificate of Analysis
- Material Safety Data Sheet
CardiovascularCell Signaling & OncologyDiabetes & MetabolismEPAC
Potent inhibitor of EPAC1
Chemical name
(R)-5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydroquinoline-1(2H)-carbaldehyde
Parent CAS No.
[1593478-56-8]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
