axonmedchem/CP 31398/10毫克/轴突2879
商品编号：
Axon2879
品牌：
axon medch
市场价：
¥1900.00
美元价：
950.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
CP 31398
Axon 2879
CAS [1217195-61-3]
MF C22H28Cl2N4OMW 435.39
- Purity:98%
- Soluble in water and DMSO
Description
CP 31398 stabilizes the core domain of the tumour suppressor p53 in vitro and is an effective anti-cancer drug by virtue of rescuing destabilized mutants of p53. Moreover, CP 31398 can induce apoptosis of human cancer cells.
KEYWORDS: CP 31398 | supplier | p53 stabilizer | CP31398 | CP-31398 | CAS [1217195-61-3] | [259199-65-0] | Non Selective | p53 | Stabilizer | Transcription Factors | Apoptosis
| BA Foster et al. Pharmacological rescue of mutant p53 conformation and function. Science. 1999 Dec 24;286(5449):2507-10. |
| TM Rippin et al. Characterization of the p53-rescue drug CP-31398 in vitro and in living cells. Oncogene. 2002 Mar 28;21(14):2119-29. |
| R Takimoto et al. The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein. Cancer Biol Ther. 2002 Jan-Feb;1(1):47-55. |
- Certificate of Analysis
- Material Safety Data Sheet
ApoptosisCell Cycle RegulationCell Signaling & OncologyStem Cellp53Transcription FactorsDNA-damage ResponseUbiquitinTF class 4.3.1
Stabilizer of p53 and inducer of apoptosis
Chemical name
(E)-N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride
Parent CAS No.
[259199-65-0]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
