axonmedchem/AS 1842856/10毫克/轴突2839
商品编号：
Axon2839
品牌：
axon medch
市场价：
¥1900.00
美元价：
950.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
AS 1842856
Axon 2839
CAS [836620-48-5]
MF C18H22FN3O3MW 347.38
- Purity:99%
- Soluble in DMSO
Description
AS 1842856 is an orally active, potent and selective inhibitor of Forkhead box protein O1 transcription factor (IC50 value of 33 nM). AS 1842856 reduces glucose production through the inhibition of glucose-6 phosphatase and phosphoenolpyruvate carboxykinase mRNA levels in a rat hepatic cell line. Therapeutic drug for treating type 2 diabetes.
KEYWORDS: AS 1842856 | supplier | FOXO1 inhibitor | AS1842856 | AS-1842856 | CAS [836620-48-5] | DNA-RNA | FOXO1 | Inhibitor | Transcription Factors | Diabetes | Forkhead box protein O1 transcription factor
| T Nagashima et al. Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice. Mol Pharmacol. 2010 Nov;78(5):961-70. |
- Certificate of Analysis
- Material Safety Data Sheet
ApoptosisCell Cycle RegulationCell Signaling & OncologyDiabetes & MetabolismTranscription FactorsTF class 3.3.1FOXO1
Inhibitor of the Forkhead box protein O1 (FOXO1)
Chemical name
5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Parent CAS No.
[836620-48-5]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
