axonmedchem/10058-F4/10毫克/轴突2222
商品编号：
Axon2222
品牌：
axon medch
市场价：
¥1600.00
美元价：
800.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
10058-F4
Axon 2222
CAS [403811-55-2]
MF C12H11NOS2MW 249.35
- Purity:99%
- Soluble in 0.1N NaOH(aq) and DMSO
Description
Small-molecule c-Myc inhibitor that induces cell-cycle arrest at G0/G1 phase in a dose-dependent manner. 10058-F4 targets c-Myc-Max, to disrupt the heterodimer and/or to prevent its formation, and abrogates various c-Myc–dependent functions, and induces myeloid differentiation of human acute myeloid leukemia.
| M.J. Huang et al. A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemia. Exp. Hematol. 2006, 34, 1480-1489. |
| H. Wang et al. Improved low molecular weight Myc-Max inhibitors. Mol. Cancer Ther. 2007, 6, 2399-2408. |
- Certificate of Analysis
- Material Safety Data Sheet
ApoptosisCell Cycle RegulationCell Signaling & Oncologyc-MYCTranscription FactorsTF class 1.3.2Stem Cell Differentiator
c-Myc inhibitor inducing cell-cycle arrest at G0/G1 phase
Chemical name
5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one
Parent CAS No.
[403811-55-2]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
