axonmedchem/AM 36二盐酸盐-CNSB002/10 mg/Axon 1113
商品编号：
Axon1113
品牌：
axon medch
市场价：
¥2900.00
美元价：
1450.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
AM 36 dihydrochloride - CNSB002
Axon 1113
CAS [199467-52-2]
MF C27H39ClN2O2.2HClMW 531.99
- Purity:98%
- Moderately soluble in water
Description
Na+ channel blocker; neuroprotective agent.
KEYWORDS: AM 36 dihydrochloride | supplier | Na+ channel Blocker | CNSB002 | AM36 |CAS[199467-52-2] | Sodium | Blocker | Ion Channels | Nav1.3 | Nav1.7 | Nav1.8 | neuropathic pain | analgesic | neuroprotective |ROS
| J. K. Callaway et al.Delayed Treatment With AM-36, a Novel Neuroprotective Agent, Reduces Neuronal Damage After Endothelin-1–Induced Middle Cerebral Artery Occlusion in Conscious Rats.Stroke. 1999, 30, 2704-2712. |
| J. KCallaway et al. Incorporation of sodium channel blocking and free radical scavenging activities into a single drug, AM-36, results in profound inhibition of neuronal apoptosis. Br. J. Pharmacol. 2001, 132, 1691–1698. |
| A. Kolosov et al. Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain. Pain Med. 2010 Jan;11(1):106-18. |
- Certificate of Analysis
- Material Safety Data Sheet
CNSPain & InflammationNav1.7UnclassifiedNav1.2Nav1.3
Na+ channel blocker
Chemical name
2,6-Di-tert-butyl-4-{4-[2-(4-chloro-phenyl)-2-hydroxy-ethyl]-piperazin-1-ylmethyl}-phenol dihydrochloride
Parent CAS No.
[199467-52-2]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
