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商品详细axonmedchem/A2793/10毫克/轴突3060
axonmedchem/A2793/10毫克/轴突3060
axonmedchem/A2793/10毫克/轴突3060
商品编号: Axon3060
品牌: axon medch
市场价: ¥1900.00
美元价: 950.00
产地: 美国(厂家直采)
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产品分类: 聚合物
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商品介绍

A2793

Based on 1 reference(s) in Google Scholar8101

Axon 3060

CAS [88349-90-0]

MF C13H12ClNO3MW 265.69

  • Purity:98%
  • Soluble in DMSO

A2793

Description

A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK) and TASK-1. A2793 may be considered as a tool to discriminate between the resting and activated channels in heterologous expression systems, and to block TRESK activated by calcineurin in the native cells, which do not express TASK-1.

KEYWORDS: A2793 | supplier | TRESK/TASK-1 inhibitor | A 2793 | A-2793 | CAS [88349-90-0] | Potassium | TRESK | TASK-1 | Inhibitor | Ion Channels | Migraine | Neuropathic pain | K2P18.1

M Lengyel et al. Chemically Modified Derivatives of the Activator Compound Cloxyquin Exert Inhibitory Effect on TRESK (K2P18.1) Background Potassium Channel. Mol Pharmacol. 2019 Jun;95(6):652-660.
  • Certificate of Analysis
  • Material Safety Data Sheet
CNSPain & InflammationTASK-1TRESKKCNK18
Inhibitor of the TRESK and TASK-1 potassium channel

Chemical name

Ethyl 2-(5-chloroquinolin-8-yloxy)acetate

Parent CAS No.

[88349-90-0]

品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来,是欧洲**的化学服务平台,专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织(CRO)进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源,提供药品研究用的Axon Ligands (TM)系列。