axonmedchem/A 784168/5毫克/轴突1816
商品编号：
Axon1816
品牌：
axon medch
市场价：
¥1900.00
美元价：
950.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
A 784168
Axon 1816
CAS [824982-41-4]
MF C19H15F6N3O3SMW 479.40
- Purity:98%
- Soluble in DMSO
Description
Potent and selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptors (IC50: 24 nM); displayed potent anti-nociceptive effects in a broad range of animal pain models upon oral dosing. This analgesic activity results from its ability to penetrate the central nervous system
| M Cui et al. TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists. J. Neurosci. 2006, 26(37), 9385-9393. |
| SB Brown et al. Tetrahydropyridine-4-carboxamides as novel, potent transient receptor potential vanilloid 1 (TRPV1) antagonists. Bioorg. Med. Chem. 2008,16, 8516–8525. |
- Certificate of Analysis
- Material Safety Data Sheet
CNSPain & InflammationTRPV1Unclassified
TRPV1 receptor antagonist
Chemical name
1-(3-(trifluoromethyl)pyridin-2-yl)-N-(4-(trifluoromethylsulfonyl)phenyl)-1,2,3,6-tetrahydropyridine-4-carboxamide
Parent CAS No.
[824982-41-4]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
