axonmedchem/ABT 239酒石酸盐/5毫克/Axon 1510
商品编号：
Axon1510
品牌：
axon medch
市场价：
¥2400.00
美元价：
1200.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
ABT 239 tartrate
Axon 1510
CAS [ 460748-71-4]
MF C22H22N2O.C4H6O6MW 480.51
- Purity:98%
- Optical purity:>98% ee
- Soluble in water and DMSO
Description
Potent and selective histamine H3 receptor antagonist or inverse agonist; a highly recommended tool for animal research into H3 antagonist / inverse agonist
| TA Esbenshade et al. Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties. J. Ph. Exp. Ther. 2005, 313, 165. |
| GB Fox et al. Pharmacological properties of ABT-239 : II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist. J. Ph. Exp. Ther. 2005, 313, 176–90. |
| M Cowart et al. 4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention. J. Med. Chem. 2005, 48 (1), 38–55. |
- Certificate of Analysis
- Material Safety Data Sheet
CNSDiabetes & MetabolismImmunologyPain & InflammationH3A18
H3 antagonist/inverse agonist
Chemical name
4-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-benzonitrile tartrate
Parent CAS No.
[460746-46-7]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
