阿维替尼/阿维替尼-AC 0010 | Avitinib/10 mg/阿维替尼3040
商品编号：
Axon3040
品牌：
axon medch
市场价：
¥1900.00
美元价：
950.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Abivertinib - AC 0010 | Avitinib
Axon 3040
CAS [1557267-42-1]
MF C26H26FN7O2MW 487.53
- Purity:99%
- Soluble in DMSO
Description
Abivertinib is a potent, selective, orally available and irreversible third-generation EGFR inhibitor with an IC50 value of 0.18 nM against EGFR L858R/T790M double mutations.
KEYWORDS: Abivertinib | supplier | EGFR inhibitor | AC 0010 | Avitinib | AC0010 | AC-0010 | CAS [1557267-42-1] | EGF | EGFR | Inhibitor | Receptors | NSCLC | T790M
| X Xu et al. AC0010, an Irreversible EGFR Inhibitor Selectively Targeting Mutated EGFR and Overcoming T790M-Induced Resistance in Animal Models and Lung Cancer Patients. Mol Cancer Ther. 2016 Nov;15(11):2586-2597. |
- Certificate of Analysis
- Material Safety Data Sheet
Cell Signaling & OncologyEGFRJAK-STATRTK class I; EC 2.7.10.1
Potent oral, irreversible, third-generation EGFR TKI with selectivity for mutant EGFRs
Chemical name
N-(3-(2-(3-Fluoro-4-(4-methylpiperazin-1-yl)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yloxy)phenyl)acrylamide
Parent CAS No.
[1557267-42-1]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
