axonmedchem/AB 1010-甲磺酸马西替尼5 mg/Axon 1419
商品编号：
Axon1419
品牌：
axon medch
市场价：
¥1400.00
美元价：
700.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
AB 1010 - Masitinib mesylate
Axon 1419
CAS [1048007-93-7]
MF C28H30N6OS.CH4O3SMW 594.75
- Purity:99%
- Soluble in water and DMSO
Description
A potent oral tyrosine kinase inhibitor, targeting c-KIT, PDGFR and FGFR3; oncology drug under clinical trial
| P Dubreuil et al. Masitinib (AB1010), a Potent and Selective Tyrosine Kinase Inhibitor Targeting KIT. Plos ONE 2009, 4(9), e7258. |
| BN Bui et al. Preliminary efficacy and safety results of masitinib administered, front line in patients with advanced GIST. A phase II study. J. Clin. Onco. 2007, 25(18S), 10025. |
| G Giamas et al. Protein kinases as targets for cancer treatment. Pharmacogenomics. 2007, 8(8), 1005-1016. |
| KA Hahn et al. Masitinib is safe and effective for the treatment of canine mast cell tumors. J. Vet. Intern. Med. 2008, 22(6), 1301-1309. |
- Certificate of Analysis
- Material Safety Data Sheet
AngiogenesisCell Signaling & OncologyPDGFRc-KITRTK class III and V; EC 2.7.10.1FGFR
PDGFR, c-KIT and FGFR3 tyrosine kinase inhibitor
Chemical name
4-(4-Methyl-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-thiazol-2-ylamino)-phenyl]-benzamide methanesulfonate
Parent CAS No.
[790299-79-5]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
