axonmedchem/Abiraterone-CB 7598/10 mg/Axon 1873
商品编号：
Axon1873
品牌：
axon medch
市场价：
¥1800.00
美元价：
900.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Abiraterone - CB 7598
Axon 1873
CAS [154229-19-3]
MF C24H31NOMW 349.51
- Purity:100%
- Optical purity:Optically pure
- Moderately soluble in DMSO
Description
Inhibitor of the steroidal enzyme 17 α-hydroxylase/C17,20 lyase (CYP17A1); a drug used in castration-resistant prostate cancer (CRPC); active component of its formulated prodrug abiraterone acetate (Axon 1874), which is also available
| G Attard et al. Selective blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer. BJU Int. 2005, 96 (9), 1241–1246. |
| JE Ang et al. CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer. Br. J. Cancer 2009, 100(5), 671–675. |
- Certificate of Analysis
- Material Safety Data Sheet
Cell Signaling & OncologyDiabetes & MetabolismEndocrinologyEC 1.14.99.9Cytochrome P450
Inhibitor of CYP17A1
Chemical name
(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Parent CAS No.
[154229-19-3]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
