axonmedchem/A 922500/5毫克/轴突2059
商品编号：
Axon2059
品牌：
axon medch
市场价：
¥2100.00
美元价：
1050.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
A 922500
Axon 2059
CAS [959122-11-3]
MF C26H24N2O4MW 428.48
- Purity:98%
- Optical purity:97% d.e.
- Soluble in DMSO
Description
Highly potent and selective diacylglycerol acyltransferase (DGAT) isomer 1 (DGAT-1) inhibitor with nanomolar potency
| G Zhao et al. Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor. J. Med. Chem. 2008, 51(3), 380-383. |
| AJ King et al. Diacylglycerol Acyltransferase 1 Inhibition Lowers Serum Triglycerides in the Zucker Fatty Rat and the Hyperlipidemic Hamster. J. Pharmacol. Exp. Ther.2009, 330(2), 526-531. |
| AJ King et al. In vivo efficacy of acyl CoA: diacylglycerol acyltransferase (DGAT) 1 inhibition in rodent models of postprandial hyperlipidemia. Eur. J. Pharmacol. 2010, 637(1-3), 155-161. |
- Certificate of Analysis
- Material Safety Data Sheet
Cell Signaling & OncologyDiabetes & MetabolismDGAT-1EC 2.3.1.20
Highly potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor
Chemical name
(1R,2R)-2-(4"-(3-phenylureido)biphenylcarbonyl)cyclopentanecarboxylic acid
Parent CAS No.
[959122-11-3]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
