axonmedchem/A 66/5毫克/轴突1831
商品编号：
Axon1831
品牌：
axon medch
市场价：
¥1900.00
美元价：
950.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
A 66
Axon 1831
CAS [1166227-08-2]
MF C17H23N5O2S2MW 393.53
- Purity:99%
- Optical purity:Optically pure
- Soluble in DMSO
Description
Potent and specific PI3K p110α inhibitor (IC50: 32 nM); highly selective for p110α over other PI3Ks and having a high degree of specificity as it does not target other protein kinases tested; highly recommended tool in researching p110α isoform
| S Jamieson et al. A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types. Biochem J. 2011, 438(Pt 1), 53–62. |
| Ashley J. Waardenberg et al. Phosphoinositide 3-Kinase (PI3K(p110α)) Directly Regulates Key Components of the Z-disc and Cardiac Structure. J. Biol. Chem. 2011, 286, 30837-30846. |
- Certificate of Analysis
- Material Safety Data Sheet
Cell Signaling & OncologyPI3KPI3K-Akt-mTOREC 2.7.1.153
PI3K inhibitor (p110-α specific)
Chemical name
(S)-N1-(2-tert-butyl-4"-methyl-4,5"-bithiazol-2"-yl)pyrrolidine-1,2-dicarboxamide
Parent CAS No.
[1166227-08-2]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
