axonmedchem/6,8-双（苄基硫基）辛酸/10 mg/Axon 2125
商品编号：
Axon2125
品牌：
axon medch
市场价：
¥2100.00
美元价：
1050.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
6,8-Bis(benzylthio)octanoic acid
Axon 2125
CAS [95809-78-2]
MF C22H28O2S2MW 388.59
- Purity:100%
- Soluble in 0.1N NaOH(aq) and DMSO
Description
A small molecular inhibitor of a mitochondrial enzyme pyruvate dehydrogenase (PDH) complex; 6,8-bis(benzylthio)octanoic acid selectively attacks the regulatory aspects of tumor cell mitochondrial metabolism, activating both apoptotic (programmed cell death) and non-apoptotic (necrosis-like) cell death pathways.
KEYWORDS: 6,8-Bis(benzylthio)octanoic acid | PDH inhibitor | CAS [95809-78-2] | Pyruvate | PDH | Inhibitor | Enzymes
| Z Zachar et al. Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo. J. Mol. Med. (Berl). 2011, 89(11), 1137-1148. |
| KC Lee et al. Formation and anti-tumor activity of uncommon in vitro and in vivo metabolites of CPI-613, a novel anti-tumor compound that selectively alters tumor energy metabolism. Drug Metab. Lett. 2011, 5(3), 163-182. |
- Certificate of Analysis
- Material Safety Data Sheet
ApoptosisDiabetes & MetabolismPDHEC 1.2.4.1
Inhibitor of mitochondrial pyruvate dehydrogenase (PDH) complex
Chemical name
6,8-Bis(benzylthio)octanoic acid
Parent CAS No.
[95809-78-2]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
