axonmedchem/4μ8C/10 mg/轴突1902
商品编号：
Axon1902
品牌：
axon medch
市场价：
¥2100.00
美元价：
1050.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
4μ8C
Axon 1902
CAS [14003-96-4]
MF C11H8O4MW 204.18
- Purity:99%
- Soluble in DMSO
Description
Potent and selective IRE1 α inhibitor (IC50: 60 nM). 4μ8C blocks substrate access to the active site of IRE1 and selectively inactivates both Xbp1 splicing and IRE1-mediated mRNA degradation.
KEYWORDS: 4μ8C | Supplier | 14003-96-4 | Axon 1902 | 4mu8C | 4u8C | IRE1 inhibitor | Axon Medchem | Axon1902 | IRE1α | splicing | RNA degradation
| BC Cross et al. The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule. Proc. Natl. Acad. Sci. USA. 2012, 109(15), E869-78. |
- Certificate of Analysis
- Material Safety Data Sheet
ApoptosisCell Signaling & OncologyEC 2.7.11.1IRE
IRE1α inhibitor
Chemical name
7-hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde
Parent CAS No.
[14003-96-4]
品牌介绍
荷兰Axon Medchem BV公司从Axon Biochemicals BV剥离出来，是欧洲＊＊的化学服务平台，专业从事合同研究和高品质的生物活性和/或药物类似分子的合成。Axon Medchem连同Axon Biochemicals公司作为医药化学领域的合同研究组织（CRO）进行商业运作。 Axon Medchem也是高价值的生命科学产品的主要来源，提供药品研究用的Axon Ligands (TM)系列。
